Allergy-Related Medication Error Reports Submitted to a Large Patient Safety Reporting System

Authors

  • Matthew Grissinger Institute for Safe Medication Practices (ISMP)
  • Michael J Gaunt Institute for Safe Medication Practices (ISMP)
  • Alexander Shilman Institute for Safe Medication Practices (ISMP)

DOI:

https://doi.org/10.33940/medical/2019.9.3

Keywords:

drug allergy, drug reaction, medication errors, medication safety, patient safety

Abstract

Medication allergies can and do cause patient harm. Managing a patient’s allergies is a challenge for institutions because failures can happen throughout the medication-use process. A total of 854 Medication Error events associated with patient allergies that occurred between July 2016 and June 2018 were reported through a large event reporting database. Analysts categorized these events into the following five stages: obtaining information from the patient, documenting allergies in the record, ordering medications, verifying orders, and administering medications. More than half (56.3%; n = 481) of the events reached the patient. Most likely to reach patients were events involving breakdowns when obtaining information from the patient (74.7%, n = 68 of 91) and administering medications (97.6%, n = 281 of 288). In reports that indicated allergies were properly documented, the majority (87.3%, n = 289 of 331) of the events that reached patients passed through two or more stages. Organizations may use this information to inform proactive efforts to implement system-based strategies to improve the medication-use process.

References

Pau AK, Morgan JE, Terlingo A. Drug allergy documentation by physicians, nurses, and medical students. Am J Hosp Pharm. 1989 Mar;46(3):570-3. PMID: 2719043.

Cantrill JA, Cottrell WN. Accuracy of drug allergy documentation. Am J Health Syst Pharm. 1997 Jul 15;54(14):1627-9. PMID: 9248608.

MacFadden DR, LaDelfa A, Leen J, Gold WL, Daneman N, Weber E, Al-Busaidi I, Petrescu D, Saltzman I, Devlin M, Andany N, Leis JA. Impact of reported beta-lactam allergy on inpatient outcomes: a multicenter prospective cohort study. Clin Infect Dis. 2016;63(7):904-10. Also available: http://dx.doi.org/10.1093/cid/ciw462. PMID: 27402820.

Mattingly TJ, Fulton A, Lumish RA, Williams AMC, Yoon S, Yuen M, Heil EL. The cost of self-reported penicillin allergy: a systematic review. J Allergy Clin Immunol Pract. 2018 Sep-Oct;6(5):1649-1654.e4. Also available: http://dx.doi.org/10.1016/j.jaip.2017.12.033. PMID: 29355644.

Medication errors associated with documented allergies . Pa Patient Saf Advis. 2008 Sep;5(3):75-80. Also available: http://patientsafety.pa.gov/ADVISORIES/Pages/200809_75.aspx.

Cook M, Ferner RE. Adverse drug reactions: who is to know? BMJ. 1993 Aug 21;307(6902):480-1. PMID: 8400931.

Harig A, Rybarczyk A, Benedetti A, Zimmerman J. Clarification of drug allergy information using a standardized drug allergy questionnaire and interview. P T. 2018 Aug;43(8):480-504. PMID: 30100688.

Radford A, Undre S, Alkhamesi NA, Darzi SA. Recording of drug allergies: are we doing enough? J Eval Clin Pract. 2007 Feb;13(1):130-7. Also available: http://dx.doi.org/10.1111/j.1365-2753.2007.00679.x. PMID: 17286735.

Burrell C, Tsourounis C, Quan D, Jue V, Tam E, Guglielmo BJ. Impact of a pharmacist-driven protocol to improve drug allergy documentation at a university hospital. Hosp Pharm. 2013 Apr;48(4):302-7. Also available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3839456. PMID: 24421479.

Rothschild JM, Churchill W, Erickson A, Munz K, Schuur JD, Salzberg CA, Lewinski D, Shane R, Aazami R, Patka J, Jaggers R, Steffenhagen A, Rough S, Bates DW. Medication errors recovered by emergency department pharmacists. Ann Emerg Med. 2010 Jun;55(6):513-21. Also available: http://dx.doi.org/10.1016/j.annemergmed.2009.10.012. PMID: 20005011.

Blegen MA, Vaughn T, Pepper G, Vojir C, Stratton K, Boyd M, Armstrong G. Patient and staff safety: voluntary reporting. Am J Med Qual. 2004 Mar-Apr;19(2):67-74. Also available: http://dx.doi.org/10.1177/106286060401900204. PMID: 15115277.

Evans SM, Berry JG, Smith BJ, Esterman A, Selim P, O'Shaughnessy J, DeWit M. Attitudes and barriers to incident reporting: a collaborative hospital study. Qual Saf Health Care. 2006 Feb;15(1):39-43. Also available: http://dx.doi.org/10.1136/qshc.2004.012559. PMID: 16456208.

Safety brief: should transdermal fentaNYL be stocked in the ED? ISMP Med Saf Alert. 2016 Oct 20;21(21):2.

Institute for Safe Medication Practices. Guidelines for the safe use of automated dispensing cabinets. Horsham (PA): Institute for Safe Medication Practices; 2019 Feb 7. 20 p. Also available: https://www.ismp.org/resources/guidelines-safe-use-automated-dispensing-cabinets.

Institute for Safe Medication Practices. Despite technology, verbal orders persist, read back is not widespread, and errors continue. ISMP Med Saf Alert. 2017 May 18;22(10):1-4. Also available: https://www.ismp.org/resources/despite-technology-verbal-orders-persist-read-back-not-widespread-and-errors-continue.

Institute For Safe Medication Practices. Relay services for telephone prescriptions. ISMP Med Saf Alert Com/Amb. 2010;9(4):1-3.

Update on use of color-coded patient wristbands. Pa Patient Saf Advis. 2006 Aug 9;(Suppl 1):1-4. Also available: http://patientsafety.pa.gov/ADVISORIES/Pages/2006sup1_01.aspx.

Color of Safety Task Force. Patient safety: color banding. Standardization and implementation manual. Harrisburg (PA): Patient Safety Authority; 18 p. Also available: http://patientsafety.pa.gov/pst/Pages/Color-Coded_Wristbands/wristband_manual.aspx.

Insitute for Safe Medication Practices. 2018-2019 targeted medication safety best practices for hospitals. Horsham (PA): Institute for Safe Medication Practices; 2017. 16 p. Also available: http://www.ismp.org/tools/bestpractices/TMSBP-for-Hospitalsv2.pdf.

Bottle of pills/medication.

Published

2019-09-16

How to Cite

Grissinger, M., Gaunt, M. J., & Shilman, A. (2019). Allergy-Related Medication Error Reports Submitted to a Large Patient Safety Reporting System. Patient Safety, 1(1), 18–27. https://doi.org/10.33940/medical/2019.9.3

Issue

Section

Original Research and Articles
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